Propanol, [2-(2-methoxymethylethoxy)methylethoxy]- (CAS 25498-49-1) — Woody Variable Note Fragrance Ingredient

Woody · Green

Propanol, [2-(2-methoxymethylethoxy)methylethoxy]-

CAS 25498-49-1

Origin
synthetic
Note
Variable
IFRA
Use with awareness
Data as of: Apr 2026

What Is Propanol, [2-(2-methoxymethylethoxy)methylethoxy]-?

This synthetic compound is a specialized ingredient used in niche fragrances and industrial applications. It’s rarely encountered directly by consumers but may appear in high-end perfumery. Its molecular structure allows unique interactions with other fragrance components, making it valuable for creating specific olfactory effects.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Safe in regulated concentrations
Requires professional formulation knowledge
CAS
25498-49-1
Formula
Mixture
MW
Variable
Odor Family
Woody · Green
Layer 1 · Enthusiast

What Does Propanol, [2-(2-methoxymethylethoxy)methylethoxy]- Smell Like?

The odor profile is complex with ethereal, slightly sweet undertones that evolve into a clean, almost metallic dryness. Imagine the crispness of chilled stainless steel blended with the faintest whisper of synthetic violets – not floral but suggesting floral adjacency. The dry-down reveals subtle woody-textile nuances resembling freshly laundered laboratory coats.

Scent Profile
Layer 2

Chemistry, Properties & Perfumer Guide

The Chemistry

A synthetic ether-alcohol compound with a branched molecular structure. The methoxy groups create steric hindrance that affects volatility patterns. Produced through controlled etherification reactions under anhydrous conditions. The specific spatial arrangement of oxygen atoms creates unique hydrogen bonding capabilities with other fragrance molecules.

Physical & Chemical Properties

Molecular WeightNot publicly specified
ComplexityModerate synthetic compound

Perfumer Guide

Note Position
Variable
Volatility
Medium-Long
Blending
Specialized
ApplicationTypical %RangeNotes
Experimental Perfumery0.5-2%Up to 5%Used for molecular texture effects
Functional Fragrances1-3%Up to 8%Provides clean modernity

Classic Accords

Tip: Use sparingly to add dimensionality to synthetic bases without dominating compositions.

Alternatives & Comparisons

1
Dipropylene glycol CAS 25265-71-8

More common solvent with similar blending properties but less olfactory impact.

2
Triethylene glycol CAS 112-27-6

Higher boiling point alternative for longer-lasting effects in base notes.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

No specific IFRA restrictions. General guidelines for glycol ethers apply.

RIFM Assessment

No specific RIFM assessment found. General alcohol safety protocols recommended.

Sustainability

Synthesized from petrochemical precursors with standard industrial processes. Energy intensive production offset by low usage requirements. Not biodegradable but typically used in minimal concentrations.

Explore Propanol, [2-(2-methoxymethylethoxy)methylethoxy]-

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References

  1. PubChem Compound Summary CID Not Specified

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 25498-49-1
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

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