Phenylethyl Alcohol (CAS 60-12-8) — Floral Top Note Fragrance Ingredient




Phenylethyl Alcohol

CAS 60-12-8

Origin
Note
IFRA
Generally safe
Data as of: Mar 2026

What Is Phenylethyl Alcohol?

Phenylethyl Alcohol is a naturally occurring aromatic compound found in rose oil and other floral scents. It’s widely used in perfumes, cosmetics, and food flavorings. This ingredient matters because it provides a sweet, rosy note that’s fundamental to many fragrance compositions and can enhance both floral and non-floral accords.

Safety Profile

GENERALLY SAFE

Generally safeUse with awarenessProfessional use
GRAS (Generally Recognized As Safe)
Approved for food and fragrance use
CAS
60-12-8
Formula
Mixture
MW
Variable
Odor Family
Layer 1 · Enthusiast

What Does Phenylethyl Alcohol Smell Like?

Phenylethyl Alcohol offers a rich, sweet, floral aroma reminiscent of rose petals with subtle honey-like undertones. It starts with a bright, slightly green top note that quickly settles into a lush heart of rosy sweetness. The dry-down reveals a soft, powdery character that blends seamlessly with other florals and musks.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Chanel No. 5(Chanel, 1921)

Used as a key floral modifier to enhance the rose-jasmine heart with its sweet, honeyed rose character.

Joy(Jean Patou, 1930)

Provides foundational rosy sweetness that supports the lavish floral bouquet.

Rose Absolute(Tom Ford, 2006)

Amplifies the natural rose character while adding depth and sweetness.

Layer 2

2D Molecular Structure

2-Phenylethanol

SMILES: OCCC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

Phenylethyl Alcohol is an aromatic primary alcohol with the formula C8H10O. It occurs naturally in rose oil, carnation, hyacinth, and other flowers. Commercially, it’s produced either by hydrogenation of styrene oxide or via microbial fermentation. The compound exists as a single stereoisomer due to its simple structure.

Physical & Chemical Properties

Boiling Point 219-221 °C
Density 1.02 g/cm³
Refractive Index 1.531-1.534

Perfumer Guide

Note Position
Heart
Volatility
Medium (2-4 hours)
Blending
Excellent
Application Typical % Range Notes
Fine Fragrance 1-5% Up to 10% Core floral component
Cosmetics 0.1-1% Up to 2% Fragrance and preservative
Flavorings 5-20 ppm Up to 50 ppm Honey-rose notes

Classic Accords

+ Rose + Vanilla = Classic Bouquet
+ Jasmine + Sandalwood = Oriental Floral

Tip: Use to add natural sweetness and rosy character without overwhelming other notes.

Alternatives & Comparisons

1
Rhodinol CAS 6812-78-8

When a more citrusy rose character is desired.

2
Phenoxyethyl Isobutyrate CAS 103-60-6

For a similar rosy effect with better stability in acidic formulations.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

No restrictions under IFRA standards.

RIFM Assessment

Approved by RIFM with no safety concerns at typical usage levels.

Sustainability

Synthetic production from petrochemical sources dominates, though fermentation routes from renewable feedstocks are emerging. Considered sustainable due to low usage requirements and biodegradability.

Explore Phenylethyl Alcohol

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Industry & Science Data

Odor Detection Threshold
1.00 ppm
in air (orthonasal)
Ref: Devos et al., Chemical Senses (1990)
Commercial Price
$8–$18/kg
synthetic grade, bulk market
Indicative 2024 pricing. Varies by purity & volume.
Global Usage Rank
#21 most used
by global fragrance volume
Source: IFRA Usage Survey 2015
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References

  1. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.
  2. Arctander, S. (1969). Perfume and Flavor Chemicals. Allured Publishing.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.

Report a data error

Ingredient Data Sheet

CAS 60-12-8

Physical Properties

Molecular Weight122.16 g/mol🔬 PubChem
LogP (Octanol-Water)1.4🔬 PubChem
Boiling Point218.2 °C🔬 EPA CompTox
Vapor Pressure0.08 mmHg @ 25°C📊 OPERA
Flash Point102 °C🔬 EPA CompTox
Involatility Index0.0078💻 Calculated
log Kp (skin permeability)-2.451💻 Calculated
SMILESC1=CC=C(C=C1)CCO🔬 PubChem

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassVery slow💻 Calculated
Persistence Score1.4 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsfloralrose• leffingwell
Functional Groupsalcoholaromatic💻 RDKit
“This material enters perfume compositions at the rate of 5-10-20%, or sometimes much more. Its low cost, versatility and general acceptability on odor, its excellent stability are factors speaking strongly in favor of this otherwise relatively weak odorant. However, its odor is clearly demonstrated in an experiment with an apparently weak crystalline fixative/odorant, such as Trichloro methyl phenyl carbonyl acetate (Trirosol, Rosetone, etc.). With 5% of the crystalline material, Phenylethylalco”📖 Arctander
Phenethyl alcohol has a characteristic rose-like odor and an initially slightly bitter taste, then sweet and reminiscent of peach.📖 Fenaroli

Flavor Notes (Arctander)

“The taste of this alcohol is sweet and Honey-rose-like at concentrations lower than 40 ppm, but tends to become unpleasantly perfumy at higher concentrations. The title alcohol finds some use in flavor”📖 Arctander

Sensory Thresholds

Odor Detection Threshold1.7899 ppm (n=25)📖 van Gemert

Regulatory Status

FEMA NumberFEMA 2858⚖️ FEMA GRAS
GRAS StatusGenerally Recognized as Safe⚖️ FEMA GRAS
IOFI ClassificationNature Identical📖 Fenaroli
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID9026342

Physical Properties

Molecular Weight 122.167 g/mol🔬 EPA CompTox
Density 1.02 g/cm^3🔬 EPA CTX
Boiling Point 219.15 °C🔬 EPA CTX
Melting Point -26.113 °C🔬 EPA CTX
Flash Point 98.31 °C🔬 EPA CTX
Refractive Index 1.536 Dimensionless📊 OPERA
Molar Volume 119.757 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 1.332 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 0.985 Log10 unitless📊 OPERA
LogD (pH 7.4) 1.41 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 6.11 Log10 unitless📊 OPERA
Water Solubility 0.175 mol/L🔬 EPA CTX
Henry's Law Constant 0 atm-m3/mole🔬 EPA CTX

Transport Properties

Vapor Pressure 0.081 mmHg🔬 EPA CTX
Viscosity 5.28 cP📊 OPERA
Surface Tension 38.751 dyn/cm📊 OPERA
Thermal Conductivity 152.631 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 20.23 Ų💻 Computed
H-Bond Donors 1 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 2 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 37.337 cm^3/mol📊 OPERA
Polarizability 14.802 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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