Methanone, (2-hydroxy-4-methoxyphenyl)phenyl- (CAS 131-57-7) — Floral Base Note Fragrance Ingredient
Methanone, (2-hydroxy-4-methoxyphenyl)phenyl-
CAS 131-57-7
What Is Methanone, (2-hydroxy-4-methoxyphenyl)phenyl-?
Methanone, (2-hydroxy-4-methoxyphenyl)phenyl- is a synthetic fragrance ingredient used in sunscreens and cosmetics for its UV-absorbing properties. It’s often found in products requiring sun protection. This ingredient matters because it provides both functional benefits and a subtle fragrance profile, making it dual-purpose in formulations.
Safety Profile
USE WITH AWARENESSWhat Does Methanone, (2-hydroxy-4-methoxyphenyl)phenyl- Smell Like?
This synthetic ingredient has a faint, clean odor with subtle floral undertones. It evolves from a slightly sweet top note to a more neutral, almost imperceptible dry-down. Its scent is often masked by other ingredients in formulations, making it more functional than aromatic.
Chemistry, Properties & Perfumer Guide
The Chemistry
Methanone, (2-hydroxy-4-methoxyphenyl)phenyl- is a synthetic UV filter belonging to the benzophenone class. It is synthesized through Friedel-Crafts acylation, reacting methoxy-substituted phenols with benzoyl chloride. Its structure allows it to absorb UV radiation effectively, making it valuable in sunscreens.
Physical & Chemical Properties
| Melting Point | 62-65 °C |
|---|---|
| Solubility | Soluble in organic solvents |
Perfumer Guide
| Application | Typical % | Range | Notes |
|---|---|---|---|
| Sunscreens | 1-5% | Up to 10% | Primarily for UV protection |
| Cosmetics | 0.5-3% | Up to 5% | Secondary fragrance role |
Classic Accords
Tip: Use in combination with other UV filters for broad-spectrum protection.
Alternatives & Comparisons
Similar UV-absorbing properties but with higher skin sensitization potential.
Safety, Regulatory & Sustainability
⚠ Regulatory Disclaimer
General reference only. Consult current IFRA Standards Library before formulating.
IFRA Status
Not restricted by IFRA.
GHS Classification
RIFM Assessment
Assessed as safe for use in current concentrations.
Sustainability
This synthetic ingredient is produced in controlled laboratory settings, minimizing environmental impact. Its stability reduces the need for frequent reapplication, contributing to sustainable product use.
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References
- PubChem. Methanone, (2-hydroxy-4-methoxyphenyl)phenyl-. PubChem
Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.
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