Cinnamaldehyde (CAS 104-55-2) — cinnamon heart Note Fragrance Ingredient

cinnamon spice

Cinnamaldehyde

CAS 104-55-2

Origin
natural
Note
heart
IFRA
Use with awareness
Data as of: Mar 2026

What Is Cinnamaldehyde?

Cinnamaldehyde is the main component that gives cinnamon its characteristic spicy-sweet aroma. You’ll find it in cinnamon sticks, baked goods, holiday candles, and many warm-spiced perfumes. This molecule matters because it creates an instant association with comfort foods and festive memories, making it a powerful emotional trigger in fragrances and flavors.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
GRAS for food use
Skin sensitizer – restricted in leave-on products
Avoid in products for sensitive skin
CAS
104-55-2
Formula
C9H8O
MW
132.16
Odor Family
cinnamon spice
Cinnamaldehyde 2D structure
Cinnamaldehyde
C9H8O
Layer 1 · Enthusiast

What Does Cinnamaldehyde Smell Like?

Cinnamaldehyde bursts forth with an intense, fiery cinnamon stick character – think freshly broken cassia bark with a volatile top note that tingles the nose. The heart develops into a rich, honeyed warmth with facets of baked apples and clove-studded oranges. As it dries down, the sharpness softens into a powdery, slightly vanillic base that lingers on skin for hours. The overall effect is simultaneously gourmand and spicy, with a radiant energy that makes it cut through complex blends.

Scent Profile

In Famous Fragrances

Fragrance associations may not reflect actual formulations.

Cinnabar(Estée Lauder, 1978)

Cinnamaldehyde provides the fiery cinnamon core that balances the floral bouquet, creating a bold oriental signature. The molecule’s tenacity allows it to persist through the drydown.

Spicebomb(Viktor & Rolf, 2012)

Used judiciously to amplify the tobacco-leather accord with its sharp spice, cinnamaldehyde adds an addictive quality that makes this modern masculine irresistible.

Angel(Mugler, 1992)

The cinnamon note (from cinnamaldehyde) cuts through the gourmand sweetness, preventing the fragrance from becoming cloying while adding festive warmth.

Jōvan Musk(Coty, 1973)

Cinnamaldehyde’s spicy edge contrasts beautifully with the animalic musk base, creating a dynamic tension that defined 1970s oriental perfumery.

Royal Copenhagen(Royal Copenhagen, 1970)

This classic fougère uses cinnamaldehyde sparingly to add warmth to its lavender-oakmoss structure, demonstrating its versatility beyond oriental compositions.

Layer 2

2D Molecular Structure

3-Phenylprop-2-enal

SMILES: O=CC=CC1=CC=CC=C1

Chemistry, Properties & Perfumer Guide

The Chemistry

Cinnamaldehyde is a phenylpropanoid, belonging to the class of α,β-unsaturated aldehydes. Naturally occurring in cinnamon bark (Cinnamomum spp.), it’s biosynthesized from phenylalanine via the shikimate pathway. Commercial production typically involves base-catalyzed condensation of benzaldehyde and acetaldehyde, yielding the trans-isomer (E-cinnamaldehyde) which is odor-active. The cis-isomer (Z-cinnamaldehyde) occurs in trace amounts and has different olfactory properties. The molecule’s reactivity stems from its conjugated carbonyl system, making it prone to oxidation and polymerization over time.

Physical & Chemical Properties

Boiling Point253 °C
Melting Point-7.5 °C
Flash Point160 °F
Density1.048-1.052 g/cm³
Vapor Pressure2.89×10⁻² mmHg
Refractive Index1.618-1.623
Solubility700 parts water
AppearanceYellowish oily liquid

Perfumer Guide

Note Position
Heart
Volatility
Medium (2-6 hours)
Blending
Good
ApplicationTypical %RangeNotes
Fine Fragrance0.1-0.5%Up to 1%Powerful modifier – use sparingly
Functional Fragrance0.01-0.1%Up to 0.2%Air fresheners, candles
Flavor10-100 ppmUp to 200 ppmBaked goods, chewing gum
Cosmetics0.01-0.05%Up to 0.1%Rinse-off products preferred

Classic Accords

+ Vanilla + Benzoin = Christmas + Cardamom + Patchouli = Spiced Oriental + Orange + Clove = Mulled Wine

Tip: Pre-dilute to 10% in DPG to prevent crystallization and improve blendability.

Alternatives & Comparisons

1
Cinnamyl Alcohol CAS 104-54-1

Milder, sweeter cinnamon character without the sharpness. Use when skin sensitivity is a concern or for softer spice effects.

2
Methyl Cinnamate CAS 103-26-4

Esterified version with fruity-balsamic nuances. More stable in alkaline formulations and less prone to oxidation.

3
Cinnamyl Acetate CAS 103-54-8

Softer, floral-spicy character with better solubility in alcohol bases. Ideal for fresh citrus colognes.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. IFRA, REACH, EU Cosmetics Regulation standards update periodically. Consult current IFRA Standards Library before formulating. Not legal or regulatory advice.

IFRA Status

Restricted to 0.05% in leave-on products (IFRA 49th Amendment). No restrictions for rinse-off products.

EU Allergen Declaration

Must be declared when present at ≥0.001% in leave-on products, ≥0.01% in rinse-off products (Annex III of EU Regulation No 1223/2009).

GHS Classification

H315 Skin irritation H317 May cause allergic skin reaction H319 Eye irritation

RIFM Assessment

RIFM assessment confirms safe use at current IFRA limits. Skin sensitization potential well-characterized.

Sustainability

Natural cinnamaldehyde is sourced from cinnamon bark distillation, primarily from Sri Lanka and Indonesia. Synthetic production avoids agricultural impacts but uses petrochemical feedstocks. Both routes are energy-intensive. Recent advances include biocatalytic production using engineered yeast strains for greener synthesis.

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References

  1. PubChem Compound Summary for CID 637511 PubChem 637511
  2. IFRA Standards Library 49th Amendment IFRA 49
  3. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Mar 2026.

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Ingredient Data Sheet

CAS 104-55-2

Physical Properties

Molecular Weight132.16 g/mol🔬 PubChem
LogP (Octanol-Water)1.9🔬 PubChem
Boiling Point253 °C🔬 EPA CompTox
Vapor Pressure2.89 mmHg @ 25°C📊 OPERA
Flash Point71.1 °C🔬 EPA CompTox
Involatility Index0.2709💻 Calculated
log Kp (skin permeability)-2.157💻 Calculated
SMILESC1=CC=C(C=C1)C=CC=O🔬 PubChem

Volatility & Performance

Fragrance NoteHeart💻 Calculated
Volatility ClassModerate💻 Calculated
Persistence Score0.5 / 5💻 Calculated

Odor & Flavor

Primary Descriptorscinnamonspicy• leffingwell
Functional Groupsaldehydealkenearomatic💻 RDKit
“Warm-spicy-balsamic odor, suggestive of Cassia-cinnamon. Good tenacity and lasting sweetness.”📖 Arctander
Cinnamaldehyde has a pungent, spicy note and burning taste.📖 Fenaroli

Flavor Notes (Arctander)

“with alcohol and most perfume and flavor oils. Sweet and warm-spicy taste with little or no Extensively used in flavor compositions.”📖 Arctander

Sensory Thresholds

Odor Detection Threshold0.9537 ppm (n=3)📖 van Gemert

Regulatory Status

IFRA ListedYes — see IFRA Standards for category limits⚖️ IFRA 51
EU Annex IIIListed (restricted)⚖️ IFRA 51
FEMA NumberFEMA 2286⚖️ FEMA GRAS
GRAS StatusGenerally Recognized as Safe⚖️ FEMA GRAS
IOFI ClassificationNature Identical📖 Fenaroli
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID1024835

Physical Properties

Molecular Weight 132.162 g/mol🔬 EPA CompTox
Density 1.05 g/cm^3🔬 EPA CTX
Boiling Point 246.667 °C🔬 EPA CTX
Melting Point -7.583 °C🔬 EPA CTX
Flash Point 83.702 °C🔬 EPA CTX
Refractive Index 1.577 Dimensionless📊 OPERA
Molar Volume 127.728 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 1.9 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 1.831 Log10 unitless📊 OPERA
LogD (pH 7.4) 1.831 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 4.83 Log10 unitless📊 OPERA
Water Solubility 0.011 mol/L🔬 EPA CTX
Henry's Law Constant 0 atm-m3/mole🔬 EPA CTX

Transport Properties

Vapor Pressure 0.037 mmHg🔬 EPA CTX
Viscosity 1.333 cP📊 OPERA
Surface Tension 36.998 dyn/cm📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 17.07 Ų💻 Computed
H-Bond Donors 0 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 2 count💻 Computed
Aromatic Rings 1 count💻 Computed
Molar Refractivity 42.329 cm^3/mol📊 OPERA
Polarizability 16.781 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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