Amyl alcohol (CAS 71-41-0) — Sweet Top Note Fragrance Ingredient

Sweet · Citrus

Amyl alcohol

CAS 71-41-0

Origin
synthetic
Note
Top
IFRA
Use with awareness
Data as of: Apr 2026

What Is Amyl alcohol?

Amyl alcohol is a synthetic alcohol commonly used as a solvent and fragrance ingredient. You might encounter it in industrial cleaners, paints, and some perfumes. While not a star ingredient, it plays a supporting role in creating certain fruity or fermented notes.

Safety Profile

USE WITH AWARENESS
Generally safeUse with awarenessProfessional use
Moderate skin irritant
Avoid inhalation of concentrated vapors
CAS
71-41-0
Formula
Mixture
MW
Variable
Odor Family
Sweet · Citrus
Layer 1 · Enthusiast

What Does Amyl alcohol Smell Like?

Amyl alcohol presents a sharp, pungent aroma reminiscent of fusel oils with distinct banana-like overtones. The initial blast is alcoholic and slightly harsh, evolving into a fermented fruity character that recalls overripe pears or amyl acetate. The dry-down reveals a lingering warmth with a faintly oily, solvent-like undertone that blends well with other fruity or woody materials.

Scent Profile
Layer 2

2D Molecular Structure

1-Pentanol

SMILES: CCCCCO

Chemistry, Properties & Perfumer Guide

The Chemistry

Amyl alcohol (pentanol) is a primary alcohol with five carbon atoms. Industrially produced via hydroformylation of butene followed by hydrogenation. Exists as several isomers including n-pentanol (1-pentanol) and isoamyl alcohol (3-methyl-1-butanol). The branched isomers are more commonly used in fragrance applications due to their more pleasant odor profiles.

Physical & Chemical Properties

Boiling Point137-138 °C
Density0.81 g/cm³
Flash Point49 °C

Perfumer Guide

Note Position
Top
Volatility
Medium (1-2 hours)
Blending
Good
ApplicationTypical %RangeNotes
Industrial Fragrance0.5-2%Up to 5%Used for solvent effects
Functional Products0.1-1%Up to 3%Masking agent

Classic Accords

Tip: Use sparingly in fruity compositions to add fermented depth without overwhelming the blend.

Alternatives & Comparisons

1
Isoamyl alcohol CAS 123-51-3

More pleasant banana-like odor profile with lower irritation potential.

2
Hexanol CAS 111-27-3

Similar functionality with greener, fresher character.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not restricted by IFRA standards.

GHS Classification

H315 Skin irritation H319 Eye irritation H335 May cause respiratory irritation

RIFM Assessment

Not currently evaluated by RIFM for fragrance use.

Sustainability

Primarily produced from petrochemical feedstocks. Considered a high-volume chemical with established production infrastructure. Limited environmental impact when properly handled, but not derived from renewable resources.

Explore Amyl alcohol

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References

  1. PubChem Compound Summary for Pentan-1-ol CID 8003
  2. Burdock, G.A. (2010). Fenaroli’s Handbook of Flavor Ingredients. CRC Press.

Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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Ingredient Data Sheet

CAS 71-41-0

Physical Properties

Molecular Weight88.15 g/mol🔬 PubChem
LogP (Octanol-Water)1.6🔬 PubChem
Boiling Point137.8 °C🔬 EPA CompTox
Vapor Pressure1 mmHg @ 25°C📊 OPERA
Flash Point32.8 °C🔬 EPA CompTox
Involatility Index0.1148💻 Calculated
log Kp (skin permeability)-2.102💻 Calculated
SMILESCCCCCO🔬 PubChem

Volatility & Performance

Fragrance NoteTop💻 Calculated
Volatility ClassModerate💻 Calculated
Persistence Score0.5 / 5💻 Calculated

Odor & Flavor

Primary Descriptorsalcoholicsolvent• leffingwell
Functional Groupsalcohol💻 RDKit
“Somewhat harsh, chemical odor, reminiscent of Fusel oil, but not as heavy, however, more penetrating, nauseating, cough-provoking. Only in high dilution fairly pleasant.”📖 Arctander
Amyl alcohol has a characteristic fusel-like sweet and pleasant odor and burning taste. It is somewhat more toxic than ethyl alcohol.📖 Fenaroli

Flavor Notes (Arctander)

“Used in flavor composition for imitation Berry, Apple, Banana, Chocolate, Pineapple, Rum and various types of Liqueur flavors, Brandy flavors, etc.”📖 Arctander

Sensory Thresholds

Odor Detection Threshold5.0162 ppm (n=10)📖 van Gemert

Regulatory Status

FEMA NumberFEMA 2056⚖️ FEMA GRAS
GRAS StatusGenerally Recognized as Safe⚖️ FEMA GRAS
IOFI ClassificationNature Identical📖 Fenaroli
Data Sources & Attribution
Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

Physicochemical Properties

DTXSID: DTXSID6021741

Physical Properties

Molecular Weight 88.15 g/mol🔬 EPA CompTox
Density 0.812 g/cm^3🔬 EPA CTX
Boiling Point 137.76 °C🔬 EPA CTX
Melting Point -80.286 °C🔬 EPA CTX
Flash Point 44.328 °C🔬 EPA CTX
Refractive Index 1.407 Dimensionless📊 OPERA
Molar Volume 108.575 cm^3/mol📊 OPERA

Partition & Solubility

LogP (Octanol-Water) 1.502 Log10 unitless🔬 EPA CTX
LogD (pH 5.5) 1.563 Log10 unitless📊 OPERA
LogD (pH 7.4) 1.563 Log10 unitless📊 OPERA
LogKoa (Octanol-Air) 4.69 Log10 unitless🔬 EPA CTX
Water Solubility 0.249 mol/L🔬 EPA CTX
Henry's Law Constant 0 atm-m3/mole🔬 EPA CTX

Transport Properties

Vapor Pressure 2.377 mmHg🔬 EPA CTX
Viscosity 2.191 cP📊 OPERA
Surface Tension 26.265 dyn/cm📊 OPERA
Thermal Conductivity 153.9 mW/(m*K)📊 OPERA

Molecular Descriptors

Topological Polar Surface Area 20.23 Ų💻 Computed
H-Bond Donors 1 count💻 Computed
H-Bond Acceptors 1 count💻 Computed
Rotatable Bonds 3 count💻 Computed
Aromatic Rings 0 count💻 Computed
Molar Refractivity 26.748 cm^3/mol📊 OPERA
Polarizability 10.604 Å^3📊 OPERA

Data Sources:

🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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