1-Methoxypropan-2-ol (CAS 107-98-2) — Sweet Carrier Note Fragrance Ingredient

ByThe Good Scents
Sweet · Citrus

1-Methoxypropan-2-ol

CAS 107-98-2

Origin
synthetic
Note
Carrier
IFRA
Professional use
Data as of: Apr 2026

What Is 1-Methoxypropan-2-ol?

1-Methoxypropan-2-ol is a synthetic solvent used in industrial applications and some fragrance formulations. It’s not commonly encountered in consumer products. This ingredient primarily serves as a carrier or modifier in technical fragrance compositions rather than as a standalone scent.

Safety Profile

PROFESSIONAL USE
Generally safeUse with awarenessProfessional use
⚠ Industrial handling precautions required
⚠ Not for direct consumer use
CAS
107-98-2
Formula
Mixture
MW
Variable
Odor Family
Sweet · Citrus
Layer 1 · Enthusiast

What Does 1-Methoxypropan-2-ol Smell Like?

This compound has minimal inherent odor characteristics, functioning primarily as a solvent rather than an aromatic component. In fragrance applications, it may carry faint ether-like notes with a clean, slightly sweet undertone. Its volatility makes it useful for temporary carrier applications rather than contributing to a fragrance’s olfactory profile.

Scent Profile
Layer 2

2D Molecular Structure

1-Methoxy-2-propanol

SMILES: COCC(C)O

Chemistry, Properties & Perfumer Guide

The Chemistry

1-Methoxypropan-2-ol is a simple ether-alcohol compound synthesized through the reaction of propylene oxide with methanol. As a small molecule with both ether and hydroxyl functional groups, it exhibits good solvent properties for various organic compounds. Its structure allows for moderate hydrogen bonding capability while maintaining sufficient volatility for certain industrial applications.

Physical & Chemical Properties

Boiling PointNot established
DensityNot established

Perfumer Guide

Note Position
Carrier
Volatility
High
Blending
Technical use only
ApplicationTypical %RangeNotes
Industrial ApplicationsVariableAs neededSolvent carrier
Technical Fragrance<5%1-10%Temporary carrier

Classic Accords

Tip: Use only in technical applications where temporary solvent properties are required.

Alternatives & Comparisons

1
Propylene Glycol CAS 57-55-6

Alternative solvent with better safety profile for cosmetic applications.

2
Dipropylene Glycol CAS 25265-71-8

Higher boiling point alternative with similar solvent properties.

Layer 3

Safety, Regulatory & Sustainability

⚠ Regulatory Disclaimer

General reference only. Consult current IFRA Standards Library before formulating.

IFRA Status

Not specifically restricted by IFRA due to industrial rather than fragrance use.

GHS Classification

H226 Flammable liquid and vapor

RIFM Assessment

Not evaluated by RIFM as it’s not a fragrance ingredient.

Sustainability

As an industrial synthetic compound, 1-Methoxypropan-2-ol is produced through petrochemical routes. Its environmental impact is primarily related to standard solvent handling precautions rather than specific sustainability concerns. Proper disposal procedures should be followed to minimize environmental release.

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References

    Data: PubChem (NIH), PubMed, RIFM, IFRA. Last reviewed: Apr 2026.

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    Ingredient Data Sheet

    CAS 107-98-2

    Physical Properties

    Molecular Weight90.12 g/mol🔬 PubChem
    LogP (Octanol-Water)-0.2🔬 PubChem
    Boiling Point120 °C🔬 EPA CompTox
    Vapor Pressure11.8 mmHg @ 25°C📊 OPERA
    Flash Point36.1 °C🔬 EPA CompTox
    Involatility Index1.3397💻 Calculated
    log Kp (skin permeability)-3.392💻 Calculated
    SMILESCC(COC)O🔬 PubChem

    Volatility & Performance

    Fragrance NoteTop💻 Calculated
    Volatility ClassFast💻 Calculated
    Persistence Score0.5 / 5💻 Calculated

    Odor & Flavor

    Primary Descriptorsetherealsweet• leffingwell
    Functional Groupsalcoholether💻 RDKit

    Sensory Thresholds

    Odor Detection Threshold27.2759 ppm (n=4)📖 van Gemert
    Data Sources & Attribution
    Physical data: PubChem (NIH/NLM), U.S. EPA CompTox Dashboard, EPA OPERA models, RDKit. Odor & flavor: Arctander (Perfume & Flavor Chemicals), Fenaroli's Handbook of Flavor Ingredients, Leffingwell. Thresholds: van Gemert (Compilations of Odour Threshold Values). Regulatory: IFRA Standards 51st, FEMA GRAS. Trade names: Surburg (Common Fragrance & Flavor Materials). All data compiled and cross-referenced for perfumertools.com.

    Physicochemical Properties

    DTXSID: DTXSID8024284

    Physical Properties

    Molecular Weight 90.122 g/mol🔬 EPA CompTox
    Density 0.934 g/cm^3🔬 EPA CTX
    Boiling Point 119.824 °C🔬 EPA CTX
    Melting Point -96.666 °C🔬 EPA CTX
    Flash Point 39.806 °C🔬 EPA CTX
    Refractive Index 1.397 Dimensionless📊 OPERA
    Molar Volume 98.808 cm^3/mol📊 OPERA

    Partition & Solubility

    LogP (Octanol-Water) -0.49 Log10 unitless🔬 EPA CTX
    LogD (pH 5.5) -0.269 Log10 unitless📊 OPERA
    LogD (pH 7.4) -0.269 Log10 unitless📊 OPERA
    LogKoa (Octanol-Air) 4.08 Log10 unitless📊 OPERA
    Water Solubility 11.095 mol/L🔬 EPA CTX
    Henry's Law Constant 0 atm-m3/mole🔬 EPA CTX

    Transport Properties

    Vapor Pressure 11.47 mmHg🔬 EPA CTX
    Viscosity 3.583 cP📊 OPERA
    Surface Tension 27.143 dyn/cm📊 OPERA
    Thermal Conductivity 159.681 mW/(m*K)📊 OPERA

    Molecular Descriptors

    Topological Polar Surface Area 29.46 Ų💻 Computed
    H-Bond Donors 1 count💻 Computed
    H-Bond Acceptors 2 count💻 Computed
    Rotatable Bonds 2 count💻 Computed
    Aromatic Rings 0 count💻 Computed
    Molar Refractivity 23.819 cm^3/mol📊 OPERA
    Polarizability 9.443 Å^3📊 OPERA

    Data Sources:

    🔬 EPA Experimental data from U.S. EPA CompTox Chemicals Dashboard & CTX APIs. 📊 OPERA Predicted using EPA's OPERA QSAR models. 💻 Computed Calculated from SMILES using RDKit.

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